Keynote Speaker: Nigel P. Weatherhill, Head of School of Engineering and Pro-Vice Chancellor (Research) Swansea University, School of Engineering, Swansea, U.K.
Talk Title: Tim Baker - His contributions to CFD

Invited Speakers:

1. isotropic surface meshing with curvature based refinement (size, curv, min_curv), 2. boundary layer meshing with limited blends and limited heuristics to deal with complex geometric interactions, 3. isotropic volume meshing with 2 to 1 transition, 4. enforce mesh size techniques to help in the transition from the boundary layer to isotropic volume meshing, 5. linear extrusion meshing.

Also, the presentation will discuss how the current SBD meshing process and desired meshing process is solver specific. In particular, how a FEA CFD solver and a finite volume CFD solver have different implicit mesh shape requirements. And as a result, what are future priorities for desired mesh techniques.

Banquet Speaker: Lawrence DeLucas, Director, UAB Center for Biophysical Sciences and Engineering

Dr. DeLucas is the Director of the Center for Biophysical Sciences and Engineering, Director and Senior Scientist of the UAB Comprehensive Cancer Center X-ray Crystallography Facility, a Professor in the School of Optometry (adjunct Professor in BioChemistry and Physiology & Biophysics), a member of the Computational and Structural Biology Core, the Center for Metabolic Bone Disease and the Laboratory of Medical Genetics at the University of Alabama at Birmingham (UAB). He currently serves as a member of the U. S. Space and Rocket Center Advisory Committee, the Illinois College of Optometry Board of Trustees, the Executive Committee of the Helen Keller Eye Research Foundation, as Co-chair of the Spacehab Science Advisory Board and is a member of the Japanese Space Agency Science Advisory Board. He is a member on the Science Advisory Boards for Bionanomatrix, Fluidigm Corporation, Diversified Scientific, Inc. and Vivo BioSciences, Inc. Among his numerous awards, Dr. DeLucas was inducted into the National Optometry Hall of Fame in 2002. Dr. DeLucas received the UAB Distinguished Faculty Lecturer award, a prestigious merit award honoring individuals in the UAB Academic Health Center who have made major contributions in education, service and drug discovery research. He received the State of Alabama Howard Heflin Statesmanship Award for Technology Innovation. He was recognized as one of the scientists who could shape the 21st Century in an article titled “The Brains Behind the 21st Century” published by “The Sunday Times” of London. He was the recipient of the Order of Rio Branco, rank of Commander from the Brazilian Government on behalf of the President of Brazil and the Grand Master of the Order of Rio Branco (1998) for the Chagas Disease Research Project. The Order of Rio Branco recognizes the merits of Brazilian and foreign individuals who have significantly contributed to the promotion of Brazil’s relations with the world.

Dr. DeLucas received 5 degrees from UAB achieving both a Doctor of Optometry and a Ph.D. degree in Biochemistry. He has also received Honorary Doctor of Science degrees from Ferris State University (May 2002), Ohio State University (June 1999), Illinois College of Optometry (May 1998), and State University of New York, College of Optometry (May 1997). He has published over 130 research articles in various peer reviewed scientific journals, co-authored two books on protein crystal growth and is an inventor /co-inventor on 15 patents mainly involving protein crystal growth and structure based drug discovery. He has been an invited lecturer at numerous US and international scientific, industrial, and governmental meetings concerning his research in protein crystallography. He was selected as one of the “Pioneers in Proteomics” by the GenomeWeb LLC publication in 2004. An early interest in microgravity research led him to qualifying as a flight Payload Specialist on the NASA Space Shuttle Columbia STS-50 mission launched in June 25, 1992. During his two week space flight mission he participated in thirty-one different scientific experiments in the areas of materials processing and fluid dynamics on the space shuttle. After his mission, Dr. DeLucas was principal investigator for a variety of microgravity experiments that were performed on 43 different shuttle flights. These experiments also resulted in the development and commercialization of hardware that reproduces conventional and novel ground based crystal growth techniques with specific adaptations made to maximize the benefits of a microgravity environment. His research utilized the experience of a large co-investigator group that consisted of scientists and engineers from universities, pharmaceutical companies, and government laboratories from around the globe. Research data from these missions have supported several successful structure based drug discovery projects for pharmaceutical and academic collaborators as well as the development of many useful research methods and novel scientific laboratory systems improving ground based research. Dr. DeLucas received the NASA Public Service Medal for exemplary performance in support of the Microgravity Projects Office in June, 1997 for his decade of service. He was also appointed and served as Chief Scientist for the International Space Station at NASA Headquarters in Washington, D.C. from 1994 to 1995.

Dr. DeLucas’ research center focuses on structure based drug discovery with x-ray crystallography in the fields of Genomics and Proteomics coupled with development and integration of innovative tools and technologies for drug discovery platforms. The Center for Biophysical Sciences and Engineering is a leading structural biology center with over 120 researchers, including 18 + in-house crystallographers. The CBSE capabilities center around a suite of commercial and proprietary High Throughput Technologies that embrace the genes to drug paradigm by attaining both speed and accuracy in the identification, optimization, and development of new therapeutics that are central to modern pharmaceutical research and development. Our drug discovery services are offered to both academic and industry partners on a cost competitive basis. The Center is part of the NIH Southeast Regional Center for Excellence in Biodefense and Emerging Infections (SERCEB), a founding member of the Southeast Regional Collaborative Access team (SERCAT) for dedicated synchrotron access and is has been involved in many multi-institutional consortiums for research in structural proteomics The CBSE is currently involved with over twenty different academic institutions and more than eight different industrial projects involving various aspects of structure base drug design.

Abstract: Space Flight and Research on the International Space Station
This presentation will illustrate Dr. DeLucas’ personal experiences as an astronaut flying on the Space Shuttle Columbia. The United States Microgravity Laboratory-1 flight, Mission STS-50, on which Dr. DeLucas was a Payload Specialist, launched on June 25, 1992 and was the longest space shuttle mission at that time (14 days). More than 30 different experiments were conducted in areas of materials processing and fluid dynamics. In addition, Dr. DeLucas will describe biotechnology experiments that have been performed on past space shuttle missions as well as planned experiments for the International Space Station. The areas of science include combustion, fluid physics, crystal growth experiments (zeolite, semiconductor, and protein), and a variety of life science investigations. Finally, Dr. DeLucas will present images of earth taken by his crew on STS-50.

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